The Miraculous Benefits of Black Cumin Oil

REVIEWED BY DR. NITA SHARMA DAS, PHD, ND, PHDHM, B

PHARM. on August 17, 2021

Written by ANDREW VON BUTZ, Natural Health Writer

EVIDENCE BASED

 

At first glance, you might mistake it for an ordinary English buttercup because of its similar appearance., but the Nigella sativa plant–which is actually the buttercup's more colorfully diverse, healing cousin–remains one of the best kept botanical       secrets of the Middle East that, chances are, is completely missing from your diet and lifestyle.

 

Locked inside every flowering center of this attractive blooming annual are precious seeds bearing a nutritive oil so amazing that more than 1,000 peer-reviewed studies (and counting!) have contributed to the revelatory tapestry of what we now know to  be  its virtually limitless therapeutic potential (as per search result found in PubMed by using the search term nigella sativa, https://www.ncbi.nlm.nih.gov/pubmed/?term=nigella+sativa)

This cherished elixir is commonly referred to as black cumin oil– or  what you might refer to as the "lifeblood" of nigella sativa seeds.

When the flower pods in which these seeds live reach their  full  maturity and open up, the initial pale color they reveal quickly darkens into a uniquely iconic shade of black. 

This is right about the time when nigella sativa seeds are ready to  be harvested and pressed, releasing what you'll soon find out is one of the most powerfully restorative functional foods on the planet–and one that many people, especially in the West, have yet to even discover.

Black cumin oil: a historical treasure

Hailing from the Ranunculaceae family of plants, Nigella sativa bears a rich history of use in ancient medicinal systems including Tibetan, Unani, Siddha and Ayurveda. [1] . Its popularity spans a multitude of cultures, religious systems, and eras, with historical records showing that both the seeds and the oil of the precious plant have long been prized items in the Arab trade.

Because of their many miraculous properties, these botanical  treasures have made their way far beyond the borders of countries like Iran and Turkey where Nigella sativa grows natively, and into whole new continents like Asia, Africa, and Europe–and perhaps most recently, North America. [2]

 

The earliest known literary reference to Nigella sativa just so happens to be in the Old Testament book of Isaiah, where it is referred to in the Hebrew tongue as "ketzah." The ancients of this early Biblical epoch are noted as having baked black cumin oil into various breads and cakes in order to procure these foods with its unique flavor and healing profile.

 

In Isaiah 28:25,27, this biblical prophet contrasts the process of harvesting Nigella sativa seeds to that of traditional wheat, explaining how rather than being threshed like typical grains, the seeds of Nigella sativa were instead beaten out of the plant using a stick or rod. [3]

 

In the Islamic tradition, the prophet Muhammed is credited as having defined black cumin oil as a miraculous healing panacea that he believed is fully capable of curing almost any ailment.

Religious records indicate that he gave specific instruction to his followers to "hold on to the use of the black seed (black seed being another common name for black cumin), for indeed it has a remedy for every disease except death." [4]

 

Though neither religion had the scientific wherewithal at the time to support such claims the way we do now, these  ancients  recognized from the common cultural and religious uses of black cumin oil that the substance is, indeed, something quite special.

 

And it was only a matter of time before black cumin oil eventually made its way into Assyrian herbal literature and other early medical publications, only to continue from there earning a formidable reputation as one of the world's most distinctive "super foods."

 

What makes black cumin oil so special? A quick primer

Widely considered to be the father of modern medicine, the  Greek  physician Hippocrates was among the first to categorically identify black cumin oil's specific health benefits. He discovered, for instance, that taking it can help to soothe the stomach and address liver disorders. 

He and his fellow healers also observed that black cumin oil is effective in promoting skin health, as well as boosting immunity and normalizing inflammation levels–hence why black cumin  oil  was later added to the renowned German medicinal plants encyclopedias that were published between the 16th and 18th centuries. [3] 

In more modern times, peer-reviewed science has uncovered even greater details and specifics into the therapeutic efficacy  of  black cumin oil. We now know, for example, that Nigella sativa seeds and their precious oil are helpful in addressing everything from nervous system disorders and gastrointestinal imbalances to respiratory ailments and even "the big C:" cancer. [1]

 

In his famous work The Canon of Medicine, Islamic philosopher Ibn Sina further wrote about how black cumin oil can help promote purification through detoxification. He noted that black cumin oil directly contributes to improving lung function,  balancing  the body's immune response, and improving overall wellbeing. [5]

 

All of this and more can be attributed to black cumin oil's impressive nutrient profile–perhaps the most noteworthy of  which  is its dense array of essential fatty acids. These include those of the polyunsaturated variety that is known to help the body produce more prostaglandin E1, a hormone-like fatty acid that's directly associated with immune system regulation, sugar metabolism, skin health, and blood circulation. Prostaglandin E1 is also said to play a vital role in helping to protect the mucosal lining of the stomach against damage and degradation. [6]

 

What's more, protocols of medicine from both Eastern and Western traditions now recognize these and many other potential health benefits arising from the use of black cumin oil. Almost every system of medicine throughout history, in fact–from traditional Ayurveda and Unani in the Far East to contemporary integrative, and "alternative" medicine systems of the West–has shown an appreciation for at least something that black cumin  oil  has to offer in terms of functional therapeutics. [1]  

What modern science has to say about black cumin oil as a viable therapeutic

Since the gold standard of contemporary, science-based medicine is the peer-review process, you're probably curious about how black cumin oil as a therapeutic stack up in terms of meeting the rigorous scientific standards of today. Well, you'll  be  pleased to know that Nigella sativa currently ranks among the most extensively studied plant species in the world. [1]

 

Furthermore, it's pharmacological potential is so immensely  vast  that it'll likely remain the subject of intense scientific scrutiny  well  into the foreseeable future–not to mention the fact that science has likely only just begun to scratch the surface in uncovering everything its full potential. 

Based on what we already know, though, it's safe to say that Nigella sativa is nothing short of a "wonder" food when it comes to its ability to improve lives and support sustained wellness. There are, in fact, different health conditions that are known to benefit from using black cumin oil–its various constituents performing more than 20 distinct pharmacological actions throughout the body. [1] 

A comprehensive review of some of the latest science on Nigella sativa that was published in the Asian Pacific Journal of Tropical Biomedicine back in 2013 [1] reveals these to include black cumin oil's effective use as a:

·         Diuretic (increases urine production)

·         Anti-hypertensive (lowers blood pressure)

·         Anti-diabetic (lowers blood sugar)

·         Anti-cancer

·         Immunomodulatory (balances immunity)

·         Analgesic (kills pain)

·         Anti-microbial

·         Anthelmintics (kills parasites)

·         Anti-inflammatory

·         Spasmolytic (relaxes muscles)

·         Bronchodilator (opens air passageways)

·         Gastro protective

·         Hepatoprotective (protects liver)

·         Renoprotective (protects kidneys)

·         Antioxidants [1]

 

 Other research has further identified black cumin oil as helping in these additional areas as well:

·      Anti-bacterial

·         Anti-ulcerative

·         Anti-cholinergic (modulates nervous system)

·         Anti-fungal

·         Anti-viral

·         Interferon-inducing (boosts immunity)

·         Leukotriene-antagonizing (supports healthy respiration)

·         Tumor necrosis factor alpha-inhibiting (fights cancer) [1]

If you were to sum it all up in one word, energizing would  probably  be the best adjective to describe black cumin oil's comprehensive mechanistic action in supporting bodily health. Islamic medicine to this very day regards it as a full-spectrum stimulant–though not in the coffee-drinking sense, but rather as a nutrient-based, metabolic motivator that helps the body to more optimally function in both an effective and efficient state. 

Phytochemicals: one of the  secrets  behind black cumin oil's incredible efficacy

While there are a number of unique compounds locked away inside black cumin oil that contribute to its profound  therapeutic  efficacy, there's one compound in particular that science has pinpointed as holding exceptional promise: thymoquinone.  Also  known as TQ, this powerful substance probably has the most extensive track record of investigatory focus when it comes to scientific research: and for good reason. [1] 

 

Since at least the 1960s, researchers have been progressively uncovering how TQ works to scavenge and neutralize damaging free radicals that cause disease, as well as to counteract chronic inflammation and eliminate cancer cells (among other important functions). Research published in the journal Biochemical Pharmacology, for instance, reveals that multiple disease  models  show benefits from the clinical application of TQ, including in the treatment of encephalomyelitis (inflammation of the brain and spinal cord), diabetes, asthma, and carcinogenesis. [7]

 

It is now becoming widely understood that inflammation is a primary factor in the formation of many chronic illnesses. And TQ's role in an address this is critical, as the substance blocks oxidative damage while preserving and supporting the function of antioxidant enzymes like catalase, glutathione peroxidase, and glutathione-S-transferase that support longevity. The anti-cancer benefits of TQ are further noteworthy, as research shows that it helps to prevent cancer cells from spreading and reproducing, as well as provokes cancer cells to "commit suicide" (apoptosis). [8]

 

TQ isn't alone in this, however. There are multiple other phytochemical compounds contained in black cumin oil that contribute even further to fighting off disease.  Combination  of  chemical constituents of Nigella sativa gives a synergistic property. [9]

 

Similar to thymoquinone, thymohydroquinone is another compound in black cumin oil that's generally regarded as one of the world's most potent natural acetylcholinesterase (AChE) inhibitors. [10] AChE inhibitors prevent the breakdown of acetylcholine, the body's primary neurotransmitter that plays a critical role in the function of both the peripheral and central nervous systems. The body's motor neurons release acetylcholine in order to activate muscles, for instance.

Acetylcholine is also required by the body and brain to  support  learning, attention span, arousal, motivation, and memory. [11] 

Synthesized AChE inhibitors are often prescribed to patients with serious brain conditions like dementia, as their purpose is to prevent the breakdown of chemicals that serve as brain fuel.  This   suggests that black cumin oil, which is naturally rich in AChE inhibiting substances, may be used as a natural alternative for addressing conditions like Alzheimer's disease, autism, schizophrenia, Parkinson's disease, myasthenia gravis (muscular weakness), postural tachycardia syndrome (blood disorder), and various other neurodegenerative health conditions. [10]

Science-based uses of black cumin oil for specific health conditions

Incorporating black cumin oil into your life can be as simple as using it like you would olive, hemp, or any other nutritive food oil. You can pour it over salad, mix it into yogurt, bake it into your favorite bread, or even just eat it by the spoonful. Topical applications of black cumin oil can similarly help to restore and moisturize skin or nourish and thicken hair. There are also a variety of specific medical applications involving black cumin oil that have strong scientific backing, including for the following uses: 

Stop superbugs in their tracks. Research out of Pakistan determined that black cumin oil is an effective remedy for Methicillin resistant Staphylococcus aureus, or MRSA, one of the deadliest "superbugs" in the world. [12] Prepared extracts of black cumin oil have shown similar efficacy in eradicating another type of deadly infection known as Helicobacter pylori–working just as effectively as conventional triple eradication therapy. [13]

 

Get rid of those nasty toxins. Scientists from Egypt found that black cumin oil functions as a powerful protector against hepato- renal toxicity, meaning it helps the liver to rid the body of  harmful  chemical toxins. Measures of various oxidative stress markers both before and after black cumin oil was introduced in tests revealed that this incredible super food helped to improve levels of toxin-eliminating enzymes while reducing others associated with disease and liver breakdown. [14]

 

Keep your blood sugar in check. Type-2 diabetics can  benefit  from consuming black cumin oil, which was found in a Saudi Arabian study to help improve blood sugar levels in patients suffering from metabolic disorders. Taking just two grams of black cumin oil per day showed effectiveness in reducing fasting glucose levels, decreasing insulin resistance, increasing beta-cell function, and reducing glycosylated hemoglobin (HbA1c) levels. [15]

 

Achieve your ideal weight. If too much fat and not enough muscle is getting you down, consider the fact that research out of Iran found that black cumin oil possesses unique anti-obesity properties. [16] Individuals who consume it regularly have a decreased risk of other obesity-related health conditions such as heart disease. [16, 17]

 

No more seizures. Individuals with epilepsy may find relief from taking black cumin oil if the results of a double-blinded crossover clinical trial, also out of Iran, are any indication. Tests on human patients revealed that black cumin oil has powerful  anticonvulsant     effects that can help to reduce both the frequency and intensity of seizure episodes, particularly in children. [18]

 

Improve the quality of your hair and skin. Besides just adding shine to hair and glow to the skin, black cumin oil offers added benefits that support the fundamental health of these two important structures of the body. Research shows that hair loss, for instance, can actually be reversed by incorporating black cumin oil into one's beauty regimen. [19] Skin conditions may  also  disappear from its use, as researchers from Iran found that black cumin oil works at least as good as the popular skin cream betamethasone (topical steroid) at decreasing the severity of hand eczema. [20]

 

Breathe full and clear. Patients with asthma or other related respiratory conditions can similarly benefit from taking black cumin oil. One animal model found that thymoquinone (TQ) in  the  oil works better than the drug fluticasone (Flonase) at targeting both allergic reactions and asthmatic symptoms. [21]Human  trials have likewise demonstrated the ability of black cumin oil to help clear the air passageway for better breathing. [22]

 

Sore throat: be gone. Acute tonsillopharyngitis and other inflammatory conditions of the throw were shown in a paper out of Indonesia to respond positively to the use of black cumin oil. This double-blind, placebo-controlled study revealed that taking just 360 milligrams of Nigella sativa extract along with 50 milligrams of Phyllanthus niruri (a tropical healing plant) resulted in substantial reductions in throat pain, as well as enhanced healing. [23]  

 

Clear out all that lung pollution. Water-based extracts of Nigella- sativa were found in yet another Iranian study to counteract the damaging effects that chemical weapons have on the lungs.

While not everyone in the world is exposed to such wartime weapons, the findings extrapolate well to other forms of "lung pollution," as black seed compounds were shown to reduce  chest wheezing while improving pulmonary function, all without the need for any additional drug treatments. [24]

 

Kick that addiction. There's been a lot of talks recently about  the  opioid epidemic and the widespread problem of addiction in many parts of the world. Well, black cumin oil can help with that, too! Taking just 500 milligram increments of Nigella sativa on a regular basis, researchers from Pakistan have found, is highly effective in helping opioid addicts to kick the habit. Not only did black cumin oil show efficacy in minimizing withdrawal symptoms, but it also demonstrated powerful appetite-inducing effects. [25] 

What cancer? Scientists in Croatia found that multiple phytochemicals in black cumin oil, including the aforementioned TQ and thymohydroquinone, are so powerfully anti-cancer in nature that they can help reduce the number of circulating tumor cells in a patient by up to 52 percent. [26] Another study involving rats found that Nigella sativa extract works just as well, [27] and enhance the chemopreventive effect of 5-fluorouracil at suppressing the growth of colon cancer cells specifically–and can be used as adjuvant therapy with many chemotherapeutic agents. It has been observed that combination of TQ with synthetic chemotherapeutic agent exerts less toxicity and reduce side effects. . These anti-tumor properties extend beyond just colon cancer to cancers of the prostate, pancreas, and lungs, yet another study found. [28]

At Kimmel Cancer University they were able to kill 80% of Pancreatic Cancer Tumors.

ACTIVATION PERFECT PRESS BLACK SEED OIL -  BUY HERE

Choosing the best quality black cumin oil  

When choosing which type of black cumin oil to purchase, it's important to pay close attention to a product's purity, processing, and packaging. 

You'll want to stick with cold-pressed varieties of black cumin oil that are processed without the use of heat or noxious chemicals, both of which can damage or disrupt the nutrients that naturally exist in delicate complexity and perfect balance within pure, freshly-pressed oil. [29] 

This means also choosing varieties that are labeled as being 100% pure "black seed oil" or "black cumin oil," without any       outside fillers or additives.

References :

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17. Seyed MohammadMousavi, AliSheikhi, Hamed KordVarkaneh, MeysamZarezadeh, JamalRahmani, AlirezaMilajerdi, Effect of Nigella sativa supplementation on obesity indices: A systematic review and meta-analysis of randomized controlled trials. Complementary Therapies in Medicine Volume 38, June 2018, Pages 48-. d.o.i https://doi.org/10.1016/j.ctim.2018.04.003. Retrieved from https://www.sciencedirect.com/science/article/pii/S0965229918300785
18. Akhondian J, Parsa A, Rakhshande H. The effect of Nigella sativa L. (black cumin seed) on intractable pediatric seizures. Med Sci Monit. 2007 Dec;13(12):CR555-9. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/18049435 
19. Ahmad M. Eid, Nagib A. Elmarzugi, Laila M. Abu Ayyash, Maher N. Sawafta, Hadeel I. Daana. A Review on the Cosmeceutical and External Applications of Nigella sativa. J Trop Med. 2017; 2017: 7092514. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735686/
20. Yousefi M, Barikbin B, Kamalinejad M, Abolhasani E, Ebadi A, Younespour S, Manouchehrian M, Hejazi S. Comparison of therapeutic effect of topical Nigella with Betamethasone and Eucerin in hand eczema. J Eur Acad Dermatol Venereol. 2013 Dec;27(12):1498-504. doi: 10.1111/jdv.12033. Epub 2012 Dec 1. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/23198836
21.  Keyhanmanesh R, Boskabady MH, Eslamizadeh MJ, Khamneh S, Ebrahimi MA. The effect of thymoquinone, the main constituent of Nigella sativa on tracheal responsiveness and white blood cell count in lung lavage of sensitized guinea pigs. Planta Med. 2010 Feb;76(3):218-22. doi: 10.1055/s-0029-1186054. Epub 2009 Aug 26. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/19711253
22. Boskabady MH, Mohsenpoor N, Takaloo L. Antiasthmatic effect of Nigella sativa in airways of asthmatic patients. Phytomedicine. 2010 Aug;17(10):707-13.doi:10.1016/j.phymed.2010.01.002. Epub 2010 Feb 10. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/20149611
23. Dirjomuljono M, Kristyono I, Tjandrawinata RR, Nofiarny D. Symptomatic treatment of acute tonsillo-pharyngitis patients with a combination of Nigella sativaand Phyllanthus niruri extract. Int J Clin Pharmacol Ther. 2008 Jun;46(6):295-306. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/18541126
24. Boskabady MH, Farhadi J. The possible prophylactic effect of Nigella sativa seed aqueous extract on respiratory symptoms and pulmonary function tests on chemical war victims: a randomized, double-blind, placebo-controlled trial. J Altern Complement Med. 2008 Nov;14(9):1137-44. doi: 10.1089/acm.2008.0049. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/18991514
25. Sangi S, Ahmed SP, Channa MA, Ashfaq M, Mastoi SM. A new and novel treatment of opioid dependence: Nigella sativa 500 mg. J Ayub Med Coll Abbottabad. 2008 Apr-Jun;20(2):118-24. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/19385474
26. Ivankovic S, Stojkovic R, Jukic M, Milos M, Milos M, Jurin M. The antitumor activity of thymoquinone and thymohydroquinone in vitro and in vivo. Exp Oncol. 2006 Sep;28(3):220-4. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/17080016
27. Salim EI, Fukushima S. Chemopreventive potential of volatile oil from black cumin (Nigella sativa L.) seeds against rat colon carcinogenesis. Nutr Cancer. 2003;45(2):195-202. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/12881014
28.  A.G.M. Mostofa, Md Kamal Hossain, Debasish Basak, Muhammad Shahdaat Bin Sayeed. Thymoquinone as a Potential Adjuvant Therapy for Cancer Treatment: Evidence from Preclinical Studies. Front Pharmacol. 2017; 8:295. Published online 2017 Jun 12. doi: 10.3389/fphar.2017.00295. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466966/
29.  Nameer Khairullah Mohammed, Mohd Yazid Abd Manap, Chin Ping Tan, Belal J. Muhialdin, 1Amaal M. Alhelli, Anis Shobirin Meor Hussin. The Effects of Different Extraction Methods on Antioxidant Properties, Chemical Composition, and Thermal Behavior of Black Seed (Nigella sativaL.) Oil. Evid Based Complement Alternat Med. 2016; 2016: 6273817. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015008/
30. Muhammad Safwan Ahamad Bustamam, Kamarul Arifin Hadithon, Ahmed Mediani, Faridah Abas, Yaya Rukayadi, Nordin Lajis, Khozirah Shaari, Intan Safinar Ismail. Stability Study of Algerian Nigella sativa Seeds Stored under Different Conditions. J Anal Methods Chem. 2017; 2017: 7891434. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309406/